Renal magnesium loss causing hypomagnesaemia and autonomous hyperparathyroidism

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Magnesium Metabolism in Hyperparathyroidism.

In an earlier, rather extensive, publication in this journal on the "Functional Pathology of Hyperparathyroidism " (1) no mention wasmade of magnesium metabolism. Data have now been collected permitting a contribution to this phase of the subject. The methods of study were the same as described in the previous paper (1). Magnesium determinations were made by the procedure outlined by Briggs (2)...

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A well-nourished alcoholic patient developed a subacute myopathy which responded rapidly to correction of severe hypomagnesaemia. The finding of profound hypocalcaemia prompted the measurement of serum magnesium. Magnesium deficiency should be looked for in any alcoholic patient with a myopathy as the prognosis seems better than in many other forms of alcoholic myopathy. Correction of the magne...

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1. Magnesium metabolism has been studied in forty-eight patients with primary hyperparathyroidism. Metabolic balance studies were undertaken in forty-three untreated patients and in fifteen patients after parathyroidectomy. The data obtained are compared with the pattern of magnesium metabolism in healthy adults, as established by analysis of collected nutritional studies. The renal handling of...

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Full Review Inherited disorders of renal hypomagnesaemia

The kidney plays a key role in the maintenance of normal magnesium balance. The distal tubule of the kidney, namely the thick ascending limb of the loop of Henle and the distal convoluted tubule, is crucial for the regulation of serum magnesium levels and body magnesium content. The identification of molecular defects related to rare inherited magnesium losing disorders has contributed greatly ...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2004

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfh029